
There are others, but these are ones i almost always use over their standard kit. Protea is an easy one replacing her not that useful 4 (imo).
#Frame subsume plus
I have a heretical Nezha build that replaces fire walker with gloom and uses the health/energy orbs dropped from the 2 plus augment + 4 to power it. so many energy orbs drop it's no problem to keep gloom up. I typically have equilibrium on this build. I have a trinity build that replaces energy vampire with gloom and uses her 1 augment so that energy orbs drop more to power it (her 2 won't replenish your energy while gloom is on anyway). I certainly hope you're replacing her 4 with gloom and would recommend using the augments for at least 2 if not all 3 of her regular powers with it.
#Frame subsume mod
absolutely requires natural talent mod for QOL. The talon strikes on mobs in the gloom field replenish your health so fast you're casting her 3 a lot. Garuda replace her 2 with gloom and you're a perpetual motion machine while spamming her 4. You get a second blueprint from Simaris and you get the parts the same way you did the first time. I have an ember build that uses gloom in place of her 1 and uses the 4 augment so there are energy orbs dropping a lot. Yes, you can build as many copies of a frame as you like. I rarely if ever use her 4 since i put gloom on her. you can constantly replenish the shield with her 2 so it doesn't matter who many mobs you're holding in gloom. I replaced Hildryn's 1 with Gloom bc it's just better than her 4 most of the time. Also, or alternatively I have equilibrium on a frame that can generate a lot of health orbs and do the pet trick with vacuum/fetch + synth fiber + synth deconstruct where they just forever pick up every health orb giving you energy. My general strategy is that gloom works great on any frame that can make energy orbs drop more or Hildryn and that builds for decent str+rng. (#s "Text"), which will appear as Spoiler: or

#Frame subsume update
Update 33.5: The Seven Crimes of Kullervo.
